Swine Flu Virus Pandemic

Swine Flu Virus Pandemic

1. Clues to a universal flu vaccine found - New York Daily News -

   New York Daily News

   Clues to a universal flu vaccine found New York Daily News Canadian researchers have found more clues that may help lead to the creation of a universal vaccine against the seasonal flu, according to a study published on Tuesday. Researchers discovered that the vaccine given against "swine flu," or the 2009 ... Swine flu vaccine may fight other virusesVancouver Sun Swine flu vaccine may fight lethal strains, BC researchers findMontreal Gazette Universal flu shot imminent?Toronto Star news Stories -CANOE all 98 news articles »

2. Mumbai college blames swine flu for admission fiasco - IBNLive.com -

   IBNLive.com

   Mumbai college blames swine flu for admission fiasco IBNLive.com The court snubbed the institute's justification that it admitted the 28-year-old afterward since it could not get any candidates within the deadline set by the board due to the swine flu panic. According to Dr Sardar Mukhtar Tabish's petition, ...

3. Inovio makes steps towards a universal flu vax - FierceVaccines -

   Inovio makes steps towards a universal flu vax FierceVaccines In flu research, the universal flu shot is the holy grail--something that will swat swine flu, slay seasonal flu, and bludgeon bird flu. Inovio Pharmaceuticals ($INO) thinks it is a step closer to the prize with a universal avian flu vax. and more »

4. Health workers to get swine flu vaccine soon - Times of India -

   RedOrbit

   Health workers to get swine flu vaccine soon Times of India HYDERABAD: Following the recent swine flu outbreak in the state, the government is all set to launch swine flu vaccination drive for healthcare workers for the second time after 2010. The state has received 50000 doses of swine flu vaccine from the ... New clues for a universal flu vaccineSydney Morning Herald Canada researchers find clues to a universal flu vaccineStraits Times H1N1 Discovery Paves Way For Universal Flu VaccineRedOrbit all 27 news articles »

5. 'Pink slime' label echoes 'swine flu' misnomer, notes economist - CattleNetwork.com -

   'Pink slime' label echoes 'swine flu' misnomer, notes economist CattleNetwork.com Just as the "swine flu" misnomer for the H1N1 virus had an economic impact on the swine industry, the pejorative "pink slime" is causing notable impact on the beef industry, said a University of Missouri Extension economist. The correct term is "lean ... and more »

6. Swine flu vax could offer universal flu protection - FierceVaccines -

   Daily Mail

   Swine flu vax could offer universal flu protection FierceVaccines Flu comes in many forms, from the mild bout of a seasonal bug that can just knock you flat for a week, to the 2009 H1N1 (swine flu) pandemic that killed thousands of people worldwide, to mutations of the H5N1 (bird flu) virus that could be weapons of ... Researchers are closer to a universal flu vaccine that can fight any version ...Daily Mail BC research brings possibility of end to seasonal flu shots with universal vaccineYahoo! News Canada (blog) all 4 news articles »

7. Bel Marra Health Supports Recent Research by the Centers for Disease Control ... - PR Web (press release) -

   Bel Marra Health Supports Recent Research by the Centers for Disease Control ... PR Web (press release) Spokesperson for Bel Marra Health, Dr. Victor Marchione says, “A vaccine that aims to improve the T-cell response will help to provide lasting immunity against multiple strains of influenza, including the seasonal flu, avian flu and swine flu. and more »

8. Free flu shot program missing for children under six - Hamilton Spectator -

   Free flu shot program missing for children under six Hamilton Spectator Dr. Allison McGeer Dr. Allison McGeer, head of infection control at Mount Sinai Hospital and an expert on swine flu, photographed in the bacteriology lab. Doctors are taking a stand when their medical advice is being ignored, says president of ... and more »

9. 132 swine flu cases reported in AP this year - IBNLive.com -

   TopNews Arab Emirates

   132 swine flu cases reported in AP this year IBNLive.com HYDERABAD: After one-year lull, the swine flu has made a come back to the state with number of victims is on the rise this year. Just four months of the year passing, the state has reported 132 cases of swine flu. The health officials say it is ... Swine Flu Stages a ComebackTopNews Arab Emirates all 2 news articles »

10. NY1 At 20: 2009 Report Re-Visits H1N1 Outbreak In NYC - NY1 -

    NY1

    NY1 At 20: 2009 Report Re-Visits H1N1 Outbreak In NYC NY1 NY1 VIDEO: In May of 2009, concerns about H1N1 - also known as swine flu - were sweeping the city. As we mark 20 years of New York 1, we take a look back at Molly Kroon's report on the outbreak from May 18, 2009. NY1 FOLLOW-UP: According to an April ... and more »

Swine Flu Virus Pandemic

1. Risk of Confirmed Guillain-Barre Syndrome Following Receipt of Monovalent Inactivated Influenza A (H1N1) and Seasonal Influenza Vaccines in the Vaccine Safety Datalink Project, 2009-2010. - Authors: Greene SK, Rett M, Weintraub ES, Li L, Yin R, Amato AA, Ho DT, Sheikh SI, Fireman BH, Daley MF, Belongia EA, Jacobsen SJ, Baxter R, Lieu TA, Kulldorff M, Vellozzi C, Lee GM Abstract An increased risk of Guillain-Barré syndrome (GBS) following administration of the 1976 swine influenza vaccine led to a heightened focus on GBS when monovalent vaccines against a novel influenza A (H1N1) virus of swine origin were introduced in 2009. GBS cases following receipt of monovalent inactivated (MIV) and seasonal trivalent inactivated (TIV) influenza vaccines in the Vaccine Safety Datalink Project in 2009-2010 were identified in electronic data and confirmed by medical record review. Within 1-42 days following vaccination, 9 cases were confirmed in MIV recipients (1.48 million doses)...

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2. Invited Commentary: Influenza Vaccine and Guillain-Barre Syndrome--Is There a Risk? - Authors: Nelson KE Abstract After a new reassortant swine influenza A H1N1 virus caused outbreaks in Mexico and the United States in 2009, a vaccine was prepared from this virus to immunize the entire US population. Surveillance for Guillain-Barré syndrome (GBS) after receipt of this vaccine was carried out in 3 populations: the Vaccine Safety Datalink Project, the 10 Centers for Disease Control and Prevention Emerging Infections Program sites, and a network of large insurance companies. These studies found a small increase of approximately 1 case of GBS per million vaccinees above the baseline rate, which is similar to that observed after administration of seasonal influenza vaccines over the past several years. Enhanced surveillance for GBS was conducted in 2009-2010 because of ...
3. Nature publishes details of bird flu strain that could spread among people - Publication of bird flu study was delayed after warnings that the information could be exploited by terroristsControversial research on a hybrid strain of bird flu that could potentially spread between humans was published on Wednesday in Nature after security restrictions on the work were lifted.Scientists created the virus by merging a mutated strain of bird flu with the "swine flu" virus that sparked a human pandemic in 2009. The hybrid strain spread easily between ferrets – the best proxy that flu researchers have for people – but was not lethal and could be controlled with antiviral drugs and bird flu vaccines.The work by Yoshihiro Kawaoka at the University of Wisconsin-Madison was submitted last year to the journal, but was delayed after the US government's biosecurity advisers s...
4. [A(H1N1)v cases of the 2009/2010 and 2010/2011 influenza seasons in the Medical and Health Sciences Centre of Debrecen University]. - Conclusion: It is an important task to protect oncohematological and organ transplant patients. Orv. Hetil., 2012, 153, 649-654. PMID: 22543220 [PubMed - in process] (Source: Orvosi Hetilap)
5. Human Infections with Novel Reassortant Influenza A(H3N2)v Viruses, United States, 2011. - Authors: Lindstrom S, Garten R, Balish A, Shu B, Emery S, Berman L, Barnes N, Sleeman K, Gubareva L, Villanueva J, Klimov A Abstract During July-December 2011, a variant virus, influenza A(H3N2)v, caused 12 human cases of influenza. The virus contained genes originating from swine, avian, and human viruses, including the M gene from influenza A(H1N1)pdm09 virus. Influenza A(H3N2)v viruses were antigenically distinct from seasonal influenza viruses and similar to proposed vaccine virus A/Minnesota/11/2010. PMID: 22516540 [PubMed - in process] (Source: Emerging Infectious Diseases)
6. Differentiated swine airway epithelial cell cultures for the investigation of influenza A virus infection and replication - Conclusions  Retinoic acid promoted ciliogenesis, whereas epidermal growth factor controlled the thickness of the pseudoepithelium. The optimal concentrations for differentiated swine cell cultures were 1·5 ng/ml epidermal growth factor and 100 nm retinoic acid. Influenza A viruses infected and productively replicated in these cultures in the absence of exogenous trypsin, suggesting that the cultures express a protease capable of activating influenza virus hemagglutinin. Differences in virus infection and replication characteristics found previously in pigs in vivo were recapitulated in the swine cultures. This system could be a useful tool for a range of applications, including investigating influenza virus species specificity, defining cell tropism of influenza viruses in the swin...

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7. Biosecurity aspects and pathogen inactivation in acidified high risk animal by-products. - Authors: Vinnerås B, Samuelson A, Emmoth E, Nyberg KA, Albihn A Abstract The aim of the study was to investigate the effects of formic acid addition to ground high risk animal by-products (ABP 1) in terms of stabilization and pathogen inactivation and to evaluate the biosecurity risk connected with the ABP 1 based combustion fuel Biomal. Laboratory studies were performed on the persistence of Salmonella Typhimurium, Bacillus cereus spores, porcine herpes virus, avian influenza virus, bovine viral diarrhea virus, equine rhinitis A virus and porcine parvovirus in Biomal at different storage times. It was shown that Salmonella and enveloped viruses were inactivated within 1 day (24 h). Bacillus cereus spores were not reduced during 147 days and the non-enveloped virus porcine parvovi...
8. Antibodies Cross-Reactive to Influenza A (H3N2) Variant Virus and Impact of 2010-11 Seasonal Influenza Vaccine on Cross-Reactive Antibodies - United States. - Authors: Abstract Since August 2011, a total of 12 human infections with influenza A (H3N2) variant viruses with genes from avian, swine, and human viruses (i.e., A [H3N2]v) that had acquired the M gene from influenza A (H1N1)pdm09 virus have been reported to CDC. Eleven of the cases occurred in children aged <10 years. In six cases, no history of recent exposure to swine was noted, suggesting that human-to-human transmission had occurred. This new gene constellation for A (H3N2)v viruses and its temporal association with an increase in human cases of A (H3N2)v highlight the need to better understand the risk for human infection with these viruses and the extent to which current seasonal vaccines might elicit cross-reactive antibodies to them. CDC conducted a preliminary analy...
9. Avian influenza A virus PB2 promotes interferon type I inducing properties of a swine strain in porcine dendritic cells. - Authors: Ocaña-Macchi M, Ricklin ME, Python S, Monika GA, Stech J, Stech O, Summerfield A Abstract The 2009 influenza A virus (IAV) pandemic resulted from reassortment of avian, human and swine strains probably in pigs. To elucidate the role of viral genes in host adaptation regarding innate immune responses, we focussed on the effect of genes from an avian H5N1 and a porcine H1N1 IAV on infectivity and activation of porcine GM-CSF-induced dendritic cells (DC). The highest interferon type I responses were achieved by the porcine virus reassortant containing the avian polymerase gene PB2. This finding was not due to differential tropism since all viruses infected DC equally. All viruses equally induced MHC class II, but porcine H1N1 expressing the avian viral PB2 induced more promi...
10. Identification of three H1N1 influenza virus groups with natural recombinant genes circulating from 1918 to 2009. - In this study, we identify a recombinant pb1 gene, a recombinant MP segment and a recombinant PA segment. The pb1 gene is recombined from two Eurasia swine H1N1 influenza virus lineages. It belongs to a H1N1 swine clade circulating in Europe and Asia from 1999 to 2009. The mosaic MP segment descends from H7 avian and H1N1 human virus lineages and pertains to a large human H1N1 virus family circulating in Asia, Europe and America from 1918 to 2007. The recombinant PA segment originated from two swine H1N1 lineages is found in a swine H1N1 group prevailing in Asia and Europe from 1999 to 2003. These results collectively falsify the hypothesis that influenza virus do not evolve by homologous recombination. Since recombination not only leads to virus genome diversity but also can alter its hos...
11. Serological evidence of swine influenza in Brazil - This study indicates that swine influenza is disseminated throughout Minas Gerais state, Brazil. (Source: Influenza and Other Respiratory Viruses)

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12. Influenza H1N1 (swine flu) vaccination: a safety surveillance feasibility study using self‐reporting of serious adverse events and pregnancy outcomes - CONCLUSIONSOverall, no significant safety issues were identified. The methodology and use of modern technologies to collect safety data from large numbers of patients was successful and could be used again in similar safety studies. (Source: British Journal of Clinical Pharmacology)
13. Study Identifies Genetic Regulators Hijacked By Avian And Swine Flu Viruses - Researchers at the University of British Columbia have identified a number of tiny but powerful "genetic regulators" that are hijacked by avian and swine flu viruses during human infection. The discovery, published in the Journal of Virology, could reveal new targets for broad-spectrum antivirals to combat current - and perhaps future - strains of influenza A viruses... (Source: Health News from Medical News Today)
14. Narcolepsy after swine flu jab studied - In this study, researchers found that 75% of the children analysed had been vaccinated against swine flu. There were 67 confirmed cases of narcolepsy, of which 46 vaccinated and seven unvaccinated cases were included in the primary analysis. This second study looked at cases of narcolepsy within “person years”. A person year represents one person exposed for a year and is a way of correcting for the various lengths of time the children were in the study before they were vaccinated or after vaccination. For example, one child studied for 18 months and another studied for six months would provide two person years of data altogether. The incidence of narcolepsy among the vaccinated children was 9.0 cases per 100,000 person years, compared with 0.7 cases per 100,000 person years in unvacci...
15. Phylodynamic inference of infectious diseases caused by HIV, enterovirus 71 and the 2009 swine-origin human influenza virus - Future Virology , April 2012, Vol. 7, No. 4, Pages 403-412. (Source: Future Virology)

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